Article
Comparative Proteomics and Functional Analysis Reveal a Role of Plasmodium falciparum Osmiophilic Bodies in Malaria Parasite Transmission.
Molecular & cellular proteomics : MCP - 1 Oct 2016
Suárez-Cortés Pablo, Sharma Vikram, Bertuccini Lucia, Costa Giulia, Bannerman Naa-Lamiley, Sannella Anna Rosa, Williamson Kim, Klemba Michael, Levashina Elena A, Lasonder Edwin, Alano Pietro
Abstract excerpt
An essential step in the transmission of the malaria parasite to the Anopheles vector is the transformation of the mature gametocytes into gametes in the mosquito gut, where they egress from the erythrocytes and mate to produce a zygote, which matures into a motile ookinete. Osmiophilic bodies are electron dense secretory organelles of the female gametocytes which discharge their contents during gamete formation,...
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