Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar.

Stem cell research - 1 Sept 2014

Dorrell Craig, Tarlow Branden, Wang Yuhan, Canaday Pamela S, Haft Annelise, Schug Jonathan, Streeter Philip R, Finegold Milton J, Shenje Lincoln T, Kaestner Klaus H, Grompe Markus

Abstract excerpt

Pancreatic Lgr5 expression has been associated with organoid-forming epithelial progenitor populations but the identity of the organoid-initiating epithelial cell subpopulation has remained elusive. Injury causes the emergence of an Lgr5(+) organoid-forming epithelial progenitor population in the adult mouse liver and pancreas. Here, we define the origin of organoid-initiating cells from mouse pancreas and liver...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviridae
Share to Cell Separation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatocytes

Share to Hydrolases

Share to Organoids

Share to Pancreas

Share to Stem Cell Transplantation

Share to Transduction, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 25151611
DOI: 10.1016/j.scr.2014.07.006
PMCID: PMC4243830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar.PMID 25151611Read ↗

Generation and Regeneration of Cells of the Liver and PancreasSemantic proximity Read ↗

The Science and Engineering of Stem Cell–Derived Organoids-Examples from Hepatic, Biliary, and Pancreatic TissuesSemantic proximity Read ↗

Establishment of intestinal organoid cultures modeling injury-associated epithelial regenerationSemantic proximity Read ↗

Single cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal treeSemantic proximity Read ↗

Stem/progenitor cells in normal physiology and disease of the pancreasSemantic proximity Read ↗

Pancreas organoid models of development and regenerationSemantic proximity Read ↗

Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and CancerSemantic proximity Read ↗

The hepatic, biliary, and pancreatic network of stem/progenitor cell niches in humans: A new reference frame for disease and regenerationSemantic proximity Read ↗

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injurySemantic proximity Read ↗

Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes.Semantic proximity Read ↗

Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ systemSemantic proximity Read ↗

Signalling pathways and transcriptional regulators orchestrating liver development and cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.