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Generation and Regeneration of Cells of the Liver and Pancreas

4 Dec 2008

Abstract excerpt

Liver and pancreas progenitors develop from endoderm cells in the embryonic foregut. Shortly after their specification, liver and pancreas progenitors rapidly acquire markedly different cellular functions and regenerative capacities. These changes are elicited by inductive signals and genetic regulatory factors that are highly conserved among vertebrates. Interest in the development and regeneration of the organs...

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Identifiers

PMID: 19056973
DOI: 10.1126/science.1161431

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