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Article

Gilbert's disease and atazanavir: from phenotype to UDP-glucuronosyltransferase haplotype.

Hepatology (Baltimore, Md.) - 1 Nov 2006

Lankisch Tim O, Moebius Ulrike, Wehmeier Michael, Behrens Georg, Manns Michael P, Schmidt Reinhold E, Strassburg Christian P

Abstract excerpt

Gilbert's disease leads to intermittent non-hemolytic hyperbilirubinemia by a reduction of hepatic bilirubin glucuronidation associated with the presence of the UDP-glucuronosyltransferase (UGT) 1A1*28 polymorphism. It is considered benign because it does not result in hepatocellular damage. However, pharmacogenetic analyses have linked UGT1A1*28 to drug toxicity and cancer predisposition. The protease inhibitor...

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Source

Identifiers

PMID: 17058217
DOI: 10.1002/hep.21361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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