Article
Metabolic functions of duplicate genes in Saccharomyces cerevisiae.
Genome research - 1 Oct 2005
Kuepfer Lars, Sauer Uwe, Blank Lars M
Abstract excerpt
The roles of duplicate genes and their contribution to the phenomenon of enzyme dispensability are a central issue in molecular and genome evolution. A comprehensive classification of the mechanisms that may have led to their preservation, however, is currently lacking. In a systems biology approach, we classify here back-up, regulatory, and gene dosage functions for the 105 duplicate gene families of...
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