Article
Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.
Development (Cambridge, England) - 1 Sept 2014
Weiss Anna-Carina, Airik Rannar, Bohnenpoll Tobias, Greulich Franziska, Foik Anna, Trowe Mark-Oliver, Rudat Carsten, Costantini Frank, Adams Ralf H, Kispert Andreas
Abstract excerpt
The vesico-ureteric junction (VUJ) forms through a complex developmental program that connects the primordium of the upper urinary tract [the nephric duct (ND)] with that of the lower urinary tract (the cloaca). The signals that orchestrate the various tissue interactions in this program are poorly understood. Here, we show that two members of the EphA subfamily of receptor tyrosine kinases, EphA4 and EphA7, are...
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