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Molecular causes of congenital anomalies of the kidney and urinary tract (CAKUT)

24 Feb 2021

Abstract excerpt

Congenital anomalies of the kidney and urinary tract (CAKUT) occur in 0.5-1/100 newborns and as a group they represent the most frequent cause for chronic kidney failure in children. CAKUT comprise clinically heterogeneous conditions, ranging from mild vesicoureteral reflux to kidney aplasia. Most forms of CAKUT share the pathophysiology of an impaired developmental interaction of the ureteric bud (UB) and the...

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PMID: 33625646
DOI: 10.1186/s40348-021-00112-0

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