Article
Assessment of EGFR mutations in circulating tumor cell preparations from NSCLC patients by next generation sequencing: toward a real-time liquid biopsy for treatment.
PloS one - 1 Jan 2014
Marchetti Antonio, Del Grammastro Maela, Felicioni Lara, Malatesta Sara, Filice Giampaolo, Centi Irene, De Pas Tommaso, Santoro Armando, Chella Antonio, Brandes Alba Ariela, Venturino Paola, Cuccurullo Franco, Crinò Lucio, Buttitta Fiamma
Abstract excerpt
INTRODUCTION: Assessment of EGFR mutation in non-small cell lung cancer (NSCLC) patients is mandatory for optimization of pharmacologic treatment. In this respect, mutation analysis of circulating tumor cells (CTCs) may be desirable since they may provide real-time information on patient's diseas...
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