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Performance evaluation of the Biocartis Idylla EGFR Mutation Test using pre-extracted DNA from a cohort of highly characterised mutation positive samples.

Journal of clinical pathology - 1 Apr 2022

Grant Jack, Stanley Anne, Balbi Kevin, Gerrard Gareth, Bennett Philip

Abstract excerpt

AIMS: Targeted therapies for non-small cell lung carcinoma (NSCLC) rely on the detection of specific genomic lesions, such as mutations within the epidermal growth factor receptor (EGFR) gene. The Biocartis Idylla platform and single-use EGFR mutation test cartridge is CE-IVD for use with formalin-fixed paraffin embedded (FFPE) tumour material, but can also function off-scope using extracted DNA as input...

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DNA
DNA Mutational Analysis
ErbB Receptors
Lung Neoplasms
Mutation

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PMID: 33514586
DOI: 10.1136/jclinpath-2020-207338

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