Article
Hereditary ovarian cancers: from BRCA mutations to clinical management. A modern appraisal.
Cancer metastasis reviews - 1 Jun 2010
Tinelli Andrea, Malvasi Antonio, Leo Giuseppe, Vergara Daniele, Pisanò Maurizio, Ciccarese Mariangela, Chiuri Vincenzo Emanuele, Lorusso Vito
Abstract excerpt
In the past few years, ovarian cancer research has focused increasingly on disease prevention; but an increasing number of women refer to gynecology and clinical genetics clinics with a family history of ovarian cancer and inherited familial mutations. The interest on the issue has increased also due to the identification of BReast CAncer1 (BRCA1) and BRCA2 genes mutations. The importance of recognizing the...
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