Article

Beyond the BRCA1/2 genes in ovarian cancer: the clinical and prognostic role of germline pathogenic variants in the ATM gene

2025-01-08

Abstract excerpt

<title>Abstract</title> <p>Ovarian Cancer (OC) prevention and early-stage detection represents a challenge due to the lack of effective surveillance. The identification of high-risk women is crucial as it provides access to prophylactic oophorectomy and reduces disease burden. Next-Generation Sequencing approaches enable the investigation of several genes associated with monogenic hereditary cancer predisposition...

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Literature Corpus work: 4bf7850f-ae5a-5143-9014-f9640637015c
DOI: 10.21203/rs.3.rs-5769485/v1

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