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Article

Polymorphism of Nrf2, an antioxidative gene, is associated with blood pressure and cardiovascular mortality in hemodialysis patients.

International journal of medical sciences - 1 Jan 2014

Shimoyama Yasuhiko, Mitsuda Yoko, Tsuruta Yoshinari, Hamajima Nobuyuki, Niwa Toshimitsu

Abstract excerpt

OBJECTIVE: Nrf2 is a transcription factor that regulates the expression of antioxidant genes. This study aimed to investigate the association of Nrf2 gene single nucleotide polymorphisms (SNPs), rs35652124 (-653A/G) and rs6721961 (-617C/A), with laboratory data and mortality in hemodialysis (HD) patients. METHODS: Blood samples were obtained from 216 HD patients (119 males and 97 females; 60 diabetics and 156...

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Identifiers

PMID: 24904228
DOI: 10.7150/ijms.8590
PMCID: PMC4045792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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