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Article

Potential mechanisms underlying the association between single nucleotide polymorphism (BRAP and ALDH2) and hypertension among elderly Japanese population.

Scientific reports - 25 Aug 2020

Shimizu Yuji, Arima Kazuhiko, Noguchi Yuko, Kawashiri Shin-Ya, Yamanashi Hirotomo, Tamai Mami, Nagata Yasuhiro, Maeda Takahiro

Abstract excerpt

Minor allele frequency (MAF) of rs3782886 (BRAP) and rs671 (ALDH2) are reported to be inversely associated with blood pressure. Another study revealed that hematopoietic activity which is evaluated by reticulocytes could influenced on hypertension status partly by indicating activity of endothelial maintenance. Therefore, to evaluate the association between genetic factor and hypertension, influence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32843694
DOI: 10.1038/s41598-020-71031-9
PMCID: PMC7447746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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