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Article

Chromatin regulation of DNA damage repair and genome integrity in the central nervous system.

Journal of molecular biology - 9 Oct 2014

Pan Ling, Penney Jay, Tsai Li-Huei

Abstract excerpt

With the continued extension of lifespan, aging and age-related diseases have become a major medical challenge to our society. Aging is accompanied by changes in multiple systems. Among these, the aging process in the central nervous system is critically important but very poorly understood. Neurons, as post-mitotic cells, are devoid of replicative associated aging processes, such as senescence and telomere...

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Identifiers

PMID: 25128619
DOI: 10.1016/j.jmb.2014.08.001
PMCID: PMC5560486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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