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Article

Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function.

American journal of physiology. Heart and circulatory physiology - 15 Oct 2014

Saxena Amit, Dobaczewski Marcin, Rai Vikrant, Haque Zaffar, Chen Wei, Li Na, Frangogiannis Nikolaos G

Abstract excerpt

Regulatory T cells (Tregs) play a pivotal role in suppressing immune responses regulating behavior and gene expression in effector T cells, macrophages, and dendritic cells. Tregs infiltrate the infarcted myocardium; however, their role the inflammatory and reparative response after myocardial infarction remains poorly understood. We used FoxP3(EGFP) reporter mice to study Treg trafficking in the infarcted heart...

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Source

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Identifiers

PMID: 25128167
DOI: 10.1152/ajpheart.00328.2014
PMCID: PMC4200341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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