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Article

Bone marrow-derived mesenchymal stem cells attenuate myocardial ischemia-reperfusion injury via upregulation of splenic regulatory T cells.

BMC cardiovascular disorders - 27 Apr 2021

Pang Ling-Xiao, Cai Wen-Wei, Li Qian, Li Heng-Jie, Fei Min, Yuan Yong-Sheng, Sheng Bin, Zhang Ke, An Rong-Cheng, Ou Ying-Wei, Zeng Wen-Jie

Abstract excerpt

BACKGROUND: Myocardial ischemia-reperfusion injury (MIRI) is the main pathological manifestation of cardiovascular diseases such as myocardial infarction. The potential therapeutic effects of bone marrow-derived mesenchymal stem cells (BM-MSCs) and the participation of regulatory T cells (Tregs) in MIRI remains to be defined. METHODS: We used the experimental acute MIRI that was induced in mice by left ascending...

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Identifiers

PMID: 33906602
DOI: 10.1186/s12872-021-02007-4
PMCID: PMC8080373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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