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Article

Molecular mechanisms of gastric cancer initiation and progression by Helicobacter pylori

16 Jan 2016

Abstract excerpt

PURPOSE OF REVIEW: Infection with the Gram-negative, microaerophilic pathogen Helicobacter pylori results in gastric cancer in a subset of infected individuals. As such, H. pylori is the only WHO classified bacterial class I carcinogen. Numerous studies have identified mechanisms by which H. pylori alters host cell signaling pathways to cause disease. The purpose of this review is to highlight recent studies that...

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PMID: 26779778
DOI: 10.1097/qco.0000000000000248

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