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Article

Regulation of Gastric Carcinogenesis by <i>Helicobacter pylori</i> Virulence Factors

15 Jan 2008

Abstract excerpt

Helicobacter pylori is the strongest known risk factor for gastric adenocarcinoma, and strains that possess the cag secretion system, which translocates the bacterial effector CagA into host cells, augment cancer risk. H. pylori strains that express the vacuolating cytotoxin or the outer membrane protein OipA are similarly associated with severe pathologic outcomes. We previously reported that an in vivo adapted...

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PMID: 18199531
DOI: 10.1158/0008-5472.can-07-0824

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