Article
Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.
Molecular and cellular biology - 1 Aug 2008
Yoon Mi-Jeong, Koo Bon-Kyoung, Song Ran, Jeong Hyun-Woo, Shin Juhee, Kim Young-Woong, Kong Young-Yun, Suh Pann-Ghill
Abstract excerpt
Intraembryonic hematopoiesis occurs at two different sites, the floor of the aorta and subaortic patches (SAPs) of the para-aortic splanchnopleura (P-Sp)/aorta-gonad-mesonephros (AGM) region. Notch1 and RBP-jkappa are critical for the specification of hematopoietic stem cells (HSCs) in Notch sign...
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