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Article

SAMSN1 Is a Tumor Suppressor Gene in Multiple Myeloma

1 Jul 2014

Abstract excerpt

Multiple myeloma (MM), a hematological malignancy characterized by the clonal growth of malignant plasma cells (PCs) in the bone marrow, is preceded by the benign asymptomatic condition, monoclonal gammopathy of undetermined significance (MGUS). Several genetic abnormalities have been identified as critical for the development of MM; however, a number of these abnormalities are also found in patients with MGUS,...

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PMID: 25117979
DOI: 10.1016/j.neo.2014.07.002

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