Article
Association between EGF and VEGF functional polymorphisms and sporadic colorectal cancer in the Malaysian population.
Genetics and molecular research : GMR - 25 Jul 2014
Lau T P, Roslani A C, Lian L H, Lee P C, Hilmi I, Goh K L, Chua K H
Abstract excerpt
Growth factors are polypeptides that are critical for the initiation, progression, and metastasis of cancer. Most tumor cells are capable of synthesizing particular growth factors leading to constitutive pathway activation in these cells through autocrine signaling. Epidermal growth factor (EGF) is a potent mitogenic peptide that exerts direct effects on the proliferation and differentiation of tumor cells in...
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