Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathogenic B‐cell receptor signaling in lymphoid malignancies: New insights to improve treatment

12 Aug 2019

Abstract excerpt

Signals emanating from the B-cell receptor (BCR) promote proliferation and survival in diverse forms of B-cell lymphoma. Precision medicine strategies targeting the BCR pathway have been generally effective in treating lymphoma, but often fail to produce durable responses in diffuse large B-cell lymphoma (DLBCL), a common and aggressive cancer. New insights into DLBCL biology garnered from genomic analyses and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31402495
DOI: 10.1111/imr.12792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathogenic B‐cell receptor signaling in lymphoid malignancies: New insights to improve treatmentPMID 31402495Read ↗

B-cell receptor signaling as a driver of lymphoma development and evolution.Semantic proximity Read ↗

Molecular complexity of diffuse large B-cell lymphoma: a molecular perspective and therapeutic implications.Semantic proximity Read ↗

Targeting B-cell receptor and PI3K signaling in diffuse large B-cell lymphomaSemantic proximity Read ↗

Regulation of B Cell Receptor Signaling and Its Therapeutic Relevance in Aggressive B-Cell LymphomasSemantic proximity Read ↗

Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCLSemantic proximity Read ↗

Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling.Semantic proximity Read ↗

Molecular pathogenesis and treatment strategy in diffuse large B-cell lymphoma.Semantic proximity Read ↗

Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphomaSemantic proximity Read ↗

New Insights into Lymphoma PathogenesisSemantic proximity Read ↗

A multiprotein supercomplex controlling oncogenic signalling in lymphoma.Semantic proximity Read ↗

Genomic alterations underlying immune privilege in malignant lymphomasSemantic proximity Read ↗

Diffuse large B cell lymphoma: using pathologic and molecular biomarkers to define subgroups for novel therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.