Article
Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet.
The Journal of endocrinology - 1 Sept 2014
Wei Jie, Sun Xia, Chen Yajie, Li Yuanyuan, Song Liqiong, Zhou Zhao, Xu Bing, Lin Yi, Xu Shunqing
Abstract excerpt
Bisphenol A (BPA) is one of the environmental endocrine disrupting chemicals, which is present ubiquitously in daily life. Accumulating evidence indicates that exposure to BPA contributes to metabolic syndrome. In this study, we examined whether perinatal exposure to BPA predisposed offspring to fatty liver disease: the hepatic manifestation of metabolic syndrome. Wistar rats were exposed to 50 μg/kg per day BPA...
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