Article

Sex-specific expression of the human NAFLD-NASH transcriptional signatures in the liver of medaka with a history of ancestral bisphenol A exposure

2024-05-21

Abstract excerpt

The progression of fatty liver disease to non-alcoholic steatohepatitis (NASH) is a leading cause of death in humans. Lifestyles and environmental chemical exposures can increase the susceptibility of humans to NASH. In humans, the presence of bisphenol A (BPA) in urine is associated with fatty liver disease, but whether ancestral BPA exposure leads to the activation of human NAFLD-NASH-associated genes in the une...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4527c718-ea84-5760-a77b-adf32c218fc1
DOI: 10.1101/2024.05.19.594843

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex-specific expression of the human NAFLD-NASH transcriptional signatures in the liver of medaka with a history of ancestral bisphenol A exposureDOI 10.1101/2024.05.19.594843Read

Medaka liver developed Human NAFLD-NASH transcriptional signatures in response to ancestral bisphenol A exposureSemantic proximity Read

The PCOS-NAFLD Multidisease Phenotype Occurred in Medaka Fish Four Generations after the Removal of Bisphenol A Exposure.Semantic proximity Read

Stable Transmission of DNA Methylation Epimutations from Germlines to the Liver and Their Association with Fatty Liver Disease in MedakaSemantic proximity Read

Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLDSemantic proximity Read

Sex differences in the progression from NAFL to NASH: a functional meta-analysis of transcriptomic studiesSemantic proximity Read

Genetic and epigenetic mechanisms of NASH.Semantic proximity Read

Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individualsSemantic proximity Read

PFHxS Exposure and the Risk of Non-Alcoholic Fatty Liver DiseaseSemantic proximity Read

Personalized therapy when tackling nonalcoholic fatty liver disease: a focus on sex, genes, and drugs.Semantic proximity Read

Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring RatsSemantic proximity Read

Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug targetSemantic proximity Read

Transcriptomic profiling of a multiethnic pediatric NAFLD cohort reveals genes and pathways associated with diseaseSemantic proximity Read