Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The PCOS-NAFLD Multidisease Phenotype Occurred in Medaka Fish Four Generations after the Removal of Bisphenol A Exposure.

Environmental science & technology - 29 Aug 2023

Chakraborty Sourav, Anand Santosh, Coe Seraiah, Reh Beh, Bhandari Ramji Kumar

Abstract excerpt

As a heterogeneous reproductive disorder, polycystic ovary syndrome (PCOS) can be caused by genetic, diet, and environmental factors. Bisphenol A (BPA) can induce PCOS and nonalcoholic fatty liver disease (NAFLD) due to direct exposure; however, whether these phenotypes persist in future unexposed generations is not currently understood. In a previous study, we observed that transgenerational NAFLD persisted in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Effects and risks of endocrine disrupting chemicals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metabolomics and Mass Spectrometry Studies

Share to Non-alcoholic Fatty Liver Disease

Share to Oryzias

Share to Phenotype

Share to Polycystic Ovary Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 37581432
DOI: 10.1021/acs.est.3c01922
PMCID: PMC10469501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The PCOS-NAFLD Multidisease Phenotype Occurred in Medaka Fish Four Generations after the Removal of Bisphenol A Exposure.PMID 37581432Read ↗

Sex-specific expression of the human NAFLD-NASH transcriptional signatures in the liver of medaka with a history of ancestral bisphenol A exposureSemantic proximity Read ↗

Medaka liver developed Human NAFLD-NASH transcriptional signatures in response to ancestral bisphenol A exposureSemantic proximity Read ↗

Stable Transmission of DNA Methylation Epimutations from Germlines to the Liver and Their Association with Fatty Liver Disease in MedakaSemantic proximity Read ↗

Sperm miR-142-3p reprogramming mediates paternal stress-induced non-alcoholic steatohepatitis in offspring ratsSemantic proximity Read ↗

Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian PCOS model.Semantic proximity Read ↗

Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet.Semantic proximity Read ↗

Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring RatsSemantic proximity Read ↗

Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthoodSemantic proximity Read ↗

Prenatal Bisphenol A Exposure in Mice Induces Multi-tissue Multi-omics Disruptions Linking to Cardiometabolic DisordersSemantic proximity Read ↗

Sperm miR‐142‐3p Reprogramming Mediates Paternal Pre‐Pregnancy Caffeine Exposure‐Induced Non‐Alcoholic Steatohepatitis in Male Offspring RatsSemantic proximity Read ↗

Early Embryonic Androgen Exposure Induces Transgenerational Epigenetic and Metabolic ChangesSemantic proximity Read ↗

Lipid Metabolism Alteration by Endocrine Disruptors in Animal Models: An OverviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.