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Article

Methods for collapsing multiple rare variants in whole-genome sequence data.

Genetic epidemiology - 1 Sept 2014

Sung Yun Ju, Korthauer Keegan D, Swartz Michael D, Engelman Corinne D

Abstract excerpt

Genetic Analysis Workshop 18 provided whole-genome sequence data in a pedigree-based sample and longitudinal phenotype data for hypertension and related traits, presenting an excellent opportunity for evaluating analysis choices. We summarize the nine contributions to the working group on collapsing methods, which evaluated various approaches for the analysis of multiple rare variants. One contributor defined a...

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Share to Genetic Variation
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Hypertension

Share to Linkage Disequilibrium

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Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 25112183
DOI: 10.1002/gepi.21820
PMCID: PMC4558905

Genes

FLT3
MAP4

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