Article
Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model.
PloS one - 1 Jan 2014
Chirakul Sunisa, Bartpho Thanatchaporn, Wongsurawat Thidathip, Taweechaisupapong Suwimol, Karoonutaisiri Nitsara, Talaat Adel M, Wongratanacheewin Surasakdi, Ernst Robert K, Sermswan Rasana W
Abstract excerpt
The Gram-negative saprophytic bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a severe infectious disease of both humans and animals. Severity of the disease is thought to be dependent on both the health status of the host, including diabetes mellitus and kidney disease, and bacterial-derived factors. To identify the bacterial factors important during an acute infection, gene expression...
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