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Article

Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis.

Microbiology (Reading, England) - 1 Aug 2004

Stevens Mark P, Haque Ashraful, Atkins Timothy, Hill Jim, Wood Michael W, Easton Anna, Nelson Michelle, Underwood-Fowler Cindy, Titball Richard W, Bancroft Gregory J, Galyov Edouard E

Abstract excerpt

Melioidosis is a severe infectious disease of animals and humans caused by the Gram-negative intracellular pathogen Burkholderia pseudomallei. An Inv/Mxi-Spa-like type III protein secretion apparatus, encoded by the B. pseudomallei bsa locus, facilitates bacterial invasion of epithelial cells, escape from endocytic vesicles and intracellular survival. This study investigated the role of the Bsa type III secretion...

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Identifiers

PMID: 15289563
DOI: 10.1099/mic.0.27146-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis.PMID 15289563Read ↗

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