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Characterization of the murine macrophage response to infection with virulent and avirulent Burkholderia species

6 Nov 2015

Abstract excerpt

BACKGROUND: Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm) are Gram-negative facultative intracellular pathogens, which are the causative agents of melioidosis and glanders, respectively. Depending on the route of exposure, aerosol or transcutaneous, infection by Bp or Bm can result in an extensive range of disease - from acute to chronic, relapsing illness to fatal septicemia. Both diseases are...

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PMID: 26545875
DOI: 10.1186/s12866-015-0593-3

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