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Article

Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape.

BMC cancer - 23 Nov 2012

Snellenberg Suzanne, De Strooper Lise M A, Hesselink Albertus T, Meijer Chris J L M, Snijders Peter J F, Heideman Daniëlle A M, Steenbergen Renske D M

Abstract excerpt

BACKGROUND: Quantitative methylation-specific PCR (qMSP) analysis for determining the methylation status of (candidate) tumor suppressor genes has potential as objective and valuable test to triage high-risk human papillomavirus (hrHPV) positive women in cervical screening. Particularly combined methylation analysis of a panel of genes shows most promising clinical performance, with sensitivity levels that equal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23176198
DOI: 10.1186/1471-2407-12-551
PMCID: PMC3517769

Genes

CADM1
MAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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