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DNA methylation markers as a triage test for identification of cervical lesions in a high risk human papillomavirus positive screening cohort

27 Sept 2018

Abstract excerpt

Objective triage strategies are required to prevent unnecessary referrals for colposcopy in population‐based screening programs using primary high‐risk human papillomavirus (hrHPV) testing. We have identified several DNA methylation markers with high sensitivity and specificity for detection of high‐grade cervical intraepithelial neoplasia or worse (CIN2+) in women referred for colposcopy. Our study assessed...

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PMID: 30259973
DOI: 10.1002/ijc.31897

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