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Article

Single nucleotide polymorphism -799C/T in matrix metalloproteinase-8 promoter region in arterial disease.

Innate immunity - 1 Jun 2012

Pradhan-Palikhe Pratikshya, Pussinen Pirkko J, Vikatmaa Pirkka, Palikhe Anil, Kivimäki Anne S, Lepäntalo Mauri, Salo Tuula, Sorsa Timo

Abstract excerpt

Arterial disease is associated with elevated serum matrix metalloproteinase (MMP)-8 concentration. We studied the role of two promoter region single nucleotide polymorphisms (SNPs) of MMP-8 gene in the arterial disease. The population comprised patients with arterial disease (n = 124) and healthy blood donors (n = 100) as a reference group for MMP-8 SNPs (-799C/T and -381A/G) genotypes and serum concentrations....

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PMID: 21994255
DOI: 10.1177/1753425911423852

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