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Article

Effects of the differential expression of ZO ‐1 and ZO ‐2 on podocyte structure and function

29 May 2018

Abstract excerpt

Glomerular podocytes in the kidney originate from columnar epithelial cells possessing tight junctions. During podocyte differentiation, tight junctions are replaced by slit diaphragms, which are formed between foot processes and function as a blood filtration barrier. Although the expression of most tight junction components is suppressed during podocyte differentiation, several components, including ZO-1 and...

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Share to Barrier Structure and Function Studies
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PMID: 29845705
DOI: 10.1111/gtc.12598

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