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Diagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients.

Diagnostic pathology - 9 Aug 2014

Ming Zizhen, Jiang Dongxian, Hu Qin, Li Xiaojing, Huang Jie, Xu Yifan, Liu Yalan, Xu Chen, Hua Xiuguo, Hou Yingyong

Abstract excerpt

BACKGROUND: The PIK3CA gene mutation was found to associate with prognosis and might affect molecular targeted therapy in esophageal carcinoma (EC). The aim of this study is to compare different methods for analyzing the PIK3CA gene mutation in EC. METHODS: Genomic DNA was extracted from 106 surgically resected EC patient tissues. The PIK3CA mutation status (exons 9 and 20) were screened by mutant-enrich liquid...

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Identifiers

PMID: 25106743
DOI: 10.1186/s13000-014-0153-4
PMCID: PMC4149237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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