Article
TP53, PIK3CA, FBXW7 and KRAS Mutations in Esophageal Cancer Identified by Targeted Sequencing.
Cancer genomics & proteomics - 1 Jan 2000
Zheng Huili, Wang Yan, Tang Chuanning, Jones Lindsey, Ye Hua, Zhang Guangchun, Cao Weihai, Li Jingwen, Liu Lifeng, Liu Zhencong, Zhang Chao, Lou Feng, Liu Zhiyuan, Li Yangyang, Shi Zhenfen, Zhang Jingbo, Zhang Dandan, Sun Hong, Dong Haichao, Dong Zhishou, Guo Baishuai, Yan H E, Lu Qingyu, Huang Xue, Chen Si-Yi
Abstract excerpt
BACKGROUND/AIM: Esophageal cancer (EC) is a common malignancy with significant morbidity and mortality. As individual cancers exhibit unique mutation patterns, identifying and characterizing gene mutations in EC that may serve as biomarkers might help predict patient outcome and guide treatment. Traditionally, personalized cancer DNA sequencing was impractical and expensive. Recent technological advancements have...
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