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Article

Concordance between PIK3CA mutations in endoscopic biopsy and surgically resected specimens of esophageal squamous cell carcinoma.

BMC cancer - 9 Jan 2017

Hatogai Ken, Fujii Satoshi, Kojima Takashi, Daiko Hiroyuki, Doi Toshihiko, Ohtsu Atsushi, Ochiai Atsushi, Takiguchi Yuichi, Yoshino Takayuki

Abstract excerpt

BACKGROUND: PIK3CA mutations are expected to be potential therapeutic targets for esophageal squamous cell carcinoma (ESCC). We aimed to clarify the concordance between PIK3CA mutations detected in endoscopic biopsy specimens and corresponding surgically resected specimens. METHODS: We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and...

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Identifiers

PMID: 28068934
DOI: 10.1186/s12885-016-3041-3
PMCID: PMC5220610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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