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Article

Correlation of phenotypic profiles using targeted proteomics identifies mycobacterial esx-1 substrates.

Journal of proteome research - 7 Nov 2014

Champion Matthew M, Williams Emily A, Pinapati Richard S, Champion Patricia A DiGiuseppe

Abstract excerpt

The Esx/WXG-100 (ESAT-6/Wss) exporters are multiprotein complexes that promote protein translocation across the cytoplasmic membrane in a diverse range of pathogenic and nonpathogenic bacterial species. The Esx-1 (ESAT-6 System-1) system mediates virulence factor translocation in mycobacterial pathogens, including the human pathogen Mycobacterium tuberculosis. Although several genes have been associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25106450
DOI: 10.1021/pr500484w
PMCID: PMC4227905

Genes

SRM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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