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Article

UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish case-control study.

Pediatric research - 1 Nov 2014

Petersen Jesper P, Overvad Kim, Hollegaard Mads V, Ebbesen Finn, Henriksen Tine B, Thorlacius-Ussing Ole, Hougaard David M, Schrøder Henrik

Abstract excerpt

BACKGROUND: Oxidative stress is a possible risk factor in the development of acute lymphoblastic leukemia (ALL) in children. Bilirubin is a potent endogenous antioxidant, and the UGT1A1*28 polymorphism is the main genetic cause of variation in plasma bilirubin in Western Europe. METHODS: In a case-control study of 665 incident cases of ALL in childhood in Denmark 1982-2010 and 1,379 controls, associations between...

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PMID: 25105254
DOI: 10.1038/pr.2014.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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