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Article

Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia.

American journal of hematology - 1 Jul 2003

Balta Gunay, Yuksek Nazmiye, Ozyurek Emel, Ertem Ulya, Hicsonmez Gonul, Altay Cigdem, Gurgey Aytemiz

Abstract excerpt

The role of methylenetetrahydrofolate reductase (MTHFR C677T), glutathione S-transferases (GSTM1 and GSTT1 null, GSTP1 Ile105Val), and cytochromes p450 (CYP1A1*2A) genotypes in the etiology of childhood leukemia was simultaneously investigated. 144 Turkish children with acute lymphoblastic leukemia (ALL) and 33 with acute nonlymphoblastic leukemia (ANLL) were studied and compared with 185 healthy pediatric...

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Share to Cytochrome P-450 CYP1A1
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12827651
DOI: 10.1002/ajh.10339

Genes

GSTT1
GSTM1
GSTP1
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia.PMID 12827651Read ↗

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Deletion of GSTM1 and T1 genes as a risk factor for development of acute leukemia.Semantic proximity Read ↗

Association between MTHFR C677T polymorphism and risk of acute lymphoblastic leukemia: a meta-analysis based on 51 case-control studies.Semantic proximity Read ↗

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Effect of GSTM1 null genotype on risk of childhood acute leukemia: a meta-analysis.Semantic proximity Read ↗

Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms.Semantic proximity Read ↗

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