Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript.

Genes & development - 15 Aug 2014

Malone Colin D, Mestdagh Claire, Akhtar Junaid, Kreim Nastasja, Deinhard Pia, Sachidanandam Ravi, Treisman Jessica, Roignant Jean-Yves

Abstract excerpt

The exon junction complex (EJC) is a highly conserved ribonucleoprotein complex that binds RNAs during splicing and remains associated with them following export to the cytoplasm. While the role of this complex in mRNA localization, translation, and degradation has been well characterized, its mechanism of action in splicing a subset of Drosophila and human transcripts remains to be elucidated. Here, we describe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Argonaute Proteins
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Gene Silencing

Share to Protein Subunits

Share to Ribonucleoproteins

Share to RNA Splicing

Source

Open in PubMed Open full text

Identifiers

PMID: 25104425
DOI: 10.1101/gad.245829.114
PMCID: PMC4197963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript.PMID 25104425Read ↗

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.Semantic proximity Read ↗

Exon Junction Complexes: Supervising the Gene Expression Assembly Line.Semantic proximity Read ↗

How genetic defects in piRNA trimming contribute to male infertility.Semantic proximity Read ↗

piRNA pathway and the potential processing site, the nuage, in the Drosophila germline.Semantic proximity Read ↗

PNLDC1 catalysis and postnatal germline function are required for piRNA trimming, LINE1 silencing, and spermatogenesis in miceSemantic proximity Read ↗

Maternal Piwi Regulates Primordial Germ Cell Development to Ensure the Fertility of Female Progeny in <i>Drosophila</i>Semantic proximity Read ↗

DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary.Semantic proximity Read ↗

PIWI proteins and PIWI-interacting RNAs in the soma.Semantic proximity Read ↗

A heterochromatin-specific RNA export pathway facilitates piRNA productionSemantic proximity Read ↗

Imp, a key regulator of transposable elements, cell growth, and differentiation genes during embryogenesisSemantic proximity Read ↗

Nonredundant functions for Aedes albopictus Piwi5 in piRNA biogenesis and transposon silencingSemantic proximity Read ↗

Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early <i>Drosophila</i> embryogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.