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Article

Association of the intronic polymorphism rs12540874 A>G of the GRB10 gene with high birth weight.

Early human development - 1 Oct 2014

González-Renteria Siblie Marbey, Sosa-Macías Martha, Rodríguez-Moran Martha, Chairez-Hernández Isaías, Lares-Aseff Ismael A, Guerrero-Romero Fernando, Galaviz-Hernández Carlos

Abstract excerpt

BACKGROUND: High birth weight (HBW) is considered a key predictor of the development of chronic diseases, such as Type 2 Diabetes (T2D). Foetal growth depends on many factors, among which placental function is critical. Some genes with expression in the placenta, such as GRB10, are known to be involved in the regulation of insulin receptor pathways and the size of mouse littermates. AIM: To evaluate whether the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25103788
DOI: 10.1016/j.earlhumdev.2014.06.012

Genes

GRB10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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