Article
DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?
BMC medical genomics - 12 Apr 2012
Turan Nahid, Ghalwash Mohamed F, Katari Sunita, Coutifaris Christos, Obradovic Zoran, Sapienza Carmen
Abstract excerpt
BACKGROUND: Infant birth weight is a complex quantitative trait associated with both neonatal and long-term health outcomes. Numerous studies have been published in which candidate genes (IGF1, IGF2, IGF2R, IGF binding proteins, PHLDA2 and PLAGL1) have been associated with birth weight, but these studies are difficult to reproduce in man and large cohort studies are needed due to the large inter individual...
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