Article
Positional Gene Cloning in Experimental Populations.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Jagodic Maja, Stridh Pernilla
Abstract excerpt
Positional cloning is a technique that identifies a trait-associated gene based on its location in the genome and involves methods such as linkage analysis, association mapping, and bioinformatics. This approach can be used for gene identification even when little is known about the molecular basis of the trait. Vast majority of traits are regulated by multiple genomic loci called quantitative trait loci (QTL)....
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