Article
Progressive fine mapping in experimental populations: an improved strategy toward positional cloning.
Journal of theoretical biology - 21 Aug 2008
Chi Xiao-Fei, Lou Xiang-Yang, Shu Qing-Yao
Abstract excerpt
Genetic mapping is one of the key steps in positional cloning. The traditional mapping strategies typically require to genotype a set of markers that are nearly evenly or randomly distributed across the genome or a region of interest. Such "grid" strategies work with low efficiency. We propose an...
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