Article
[Mutation of MTCYB and MTATP6 is associated with asthenospermia].
Zhonghua nan ke xue = National journal of andrology - 1 Apr 2008
Feng Chun-Qiong, Song Yan-Bin, Zou Ya-Guang, Mao Xiang-Ming
Abstract excerpt
OBJECTIVE: To explore the correlation of the mutation of MTCYB and MTATP6 genes in sperm mitochondria with asthenospermia. METHODS: We extracted mtDNA from 80 semen samples of asthenospermia and 20 of normal sperm motility, amplified the MTCYB and MTATP6 genes by PCR, and analyzed their mutation by sequencing and BLAST matching. RESULTS: The deletion of both MTCYB and MTATP6 were detected in 20 of the 80...
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