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Mitochondrial variations in the MT-ND4 and MT-TL1 genes are associated with male infertility.

Systems biology in reproductive medicine - 1 Feb 2017

Ni Feng, Zhou Yun, Zhang Wen-Xiang, Wang Xue-Mei, Song Xiao-Min, Jiang Hong

Abstract excerpt

Mitochondrial gene mutations have been reported to be associated with sperm motility and the quality of semen. The aim of this study was to investigate whether the two mitochondrial genes (MT-ND4 and MT-TL1) are involved in Chinese male infertility. A total of 97 asthenospermia patients and 80 fertile controls were recruited in this case-control study. Genomic DNA were extracted from the sperm of all...

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PMID: 27973917
DOI: 10.1080/19396368.2016.1256451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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