Article
Identifying potential pitfalls in interpreting mitochondrial DNA mutations of male infertility cases.
The Indian journal of medical research - 1 Oct 2011
Palanichamy Malliya Gounder, Zhang Ya-Ping
Abstract excerpt
BACKGROUND & OBJECTIVES: Recently, a significantly higher ratio of nucleotide changes in the mtDNA genes: COII, ATPase 6, ATPase 8, ND2, ND3, ND4, and ND5 was reported in spermatozoa from populations of infertile Indian men, compared suggesting that screening for mtDNA mutations could provide insight into the aetiology of male infertility. In this study, we examined the published data and found serious errors in...
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