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Article

Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.

Development (Cambridge, England) - 1 Aug 2014

Maurer Kate A, Riesenberg Amy N, Brown Nadean L

Abstract excerpt

Notch signaling regulates basic helix-loop-helix (bHLH) factors as an evolutionarily conserved module, but the tissue-specific mechanisms are incompletely elucidated. In the mouse retina, bHLH genes Atoh7 and Neurog2 have distinct functions, with Atoh7 regulating retinal competence and Neurog2 required for progression of neurogenesis. These transcription factors are extensively co-expressed, suggesting similar...

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Identifiers

PMID: 25100656
DOI: 10.1242/dev.106245
PMCID: PMC4197552

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Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.PMID 25100656Read ↗

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