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Article

Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development.

Developmental biology - 1 Jan 2011

Mao Chai-An, Tsai Wen-Wei, Cho Jang-Hyeon, Pan Ping, Barton Michelle Craig, Klein William H

Abstract excerpt

As neuronal progenitors differentiate into neurons, they acquire a unique set of transcription factors. The transcriptional repressor REST prevents progenitors from undergoing differentiation. Notably, REST binding sites are often associated with retinal ganglion cell (RGC) genes whose expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20969844
DOI: 10.1016/j.ydbio.2010.10.008
PMCID: PMC2993882

Genes

REST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20969844-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development.PMID 20969844Read ↗

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Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate.Semantic proximity Read ↗

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