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iTRAQ-Based and Label-Free Proteomics Approaches for Studies of Human Adenovirus Infections

11 Mar 2013

Abstract excerpt

Both isobaric tags for relative and absolute quantitation (iTRAQ) and label-free methods are widely used for quantitative proteomics. Here, we provide a detailed evaluation of these proteomics approaches based on large datasets from biological samples. iTRAQ-label-based and label-free quantitations were compared using protein lysate samples from noninfected human lung epithelial A549 cells and from cells infected...

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PMID: 23555056
DOI: 10.1155/2013/581862

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